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Acetyl Aspartic acid

N-Acetyl-L-Aspartic acid

N-Acetyl-L-aspartic acid, abbreviated as NAA, is second most abundant molecule in nervous systems after amino acid glutamate. It is synthesized in brain from aspartic acid and acetyl co-enzyme A. It also acts as nutrient.

In a biological process, NAA is produced from rat brain acetone. Commercially, it is manufactured by acetylation of L-aspartic acid bis(trimethylsilyl)ester using acetyl chloride.

Synonyms N-Acetyl aspartate
CAS no. 997-55-7
EINECS no. 213-643-9
Molecular formula C6H9NO5
Molecular weight 175.14

Applications in Synthesis

The chiral acid is used to synthesize:
Its anhydride
Homoserine gamma-lactones

Other Applications

As reagent in selective reductions of cyclic ketones
In acid-catalyzed cyclization reactions
In peptide synthesis
As a nutraceutical supplement in capsule, tablet, and liquid dosage form
As antioxidant
As human and rat metabolites
Isotopic form used in studies for metabolic alteration associated with schizophrenia


Test Unit Specification
Appearance White powder
Specific rotation (C = 1, HAc) Degree 50.0 – 54.0
Water % Max 0.5
Assay % Min 98.0

The product is stored at ambient temperature.

25 kg Fibre drum.

REACH Status
Not Registered yet.