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Manufacturing Services in Switzerland

Services

Together with our longstanding network of carefully selected SWISS associates and unique subcontractors (CRO/CDMO) that are fully committed to comply with our various agreements and policies we are offering a reliable, comprehensive and transparent service for:

Custom / Contract Manufacturing (cGMP and non-GMP)
Custom synthesis on FTE & FFS service model (CRO)
Literature and Patent Research
Process Research
Process Development
Bench-Scale Lab, Kilo Lab and Pilot Plant Development
Process Optimization
Commercial manufacturing

Core Technologies

Acylation
Amination
Azidation
Bromination
Carboxylation
Chlorination
Chlorosulfonation
Dehalogenation
Diazotisation
Diels-Alder
Etherification
Friedel-Crafts
Grignard
Heterocyclic Synthesis
Hydrogenation
Mannich
Nitration
Oxidation
Phosgenation
Reduction
Sulfonation
Thiocarbonylation
Tosylation

Multipurpose Plants

Multipurpose Plants: 
40 m3 total reactor-capacity. 11 stainless steel units (450 - 4500 L), 6 glass lined units (2000 – 4900 L), 1 glass lined pressure reactor up to 24 bars suitable also for hydrogenations.

Several scrubbers to retain corrosive gases.

2 Distillation columns (up to 5 m3/h), 1 wiped film distillation (up to 700 L/h), 2 extraction columns.

4 centrifuges (200 - 400 kg), 1 suction filter dryer (1 m2), 1 vacuum paddle dryer (6000 L), 1 vacuum tray dryer (20 m2, corrosion resistant). 2 clean rooms (ISO 8) for API and API intermediates isolation and packaging.

Pilot: 
120 L glass reactor with distillation column, 120 L and 450 L stainless steel, 270 L glass lined pressure reactor up to 6 bars also suitable for hydrogenations.

Scrubber to retain corrosive gases.

Suction filter 60 L, pressure filter 100 L. Corrosion resistant vacuum tray dryer.

Clean room (ISO 8) for API and API intermediates isolation and packaging.


Phosgenation: 
Modern phosgene generator, 4500 L glass lined reactor in special isolated and dedicated containment featuring state of the art safety standards.

10-40 kg phosgene/h

Further we have extensive expertise in


Innovative green chemical solutions
based on sugar-based technology
(such as 5-HMF, FDME, DFF, PEF)

Clinical API development of small molecules and nanoparticulated non-biological complex drugs (NBCD’s). Complete service including otimizing, validation and transfer of process related analytical methods in GMP qualified laboratories could be provided.

Synthesis of super fine chemicals including fluorescent substances, bioactive molecules, organic pollutants & pesticides or pharma actives in milligrams to kilograms under non-GMP conditions.

Nano chemistry support for specific projects