Ferrozine
Ferrozine, chemically 3-(2-Pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine disodium salt, is a water-soluble solid. It is complexometric reagent for detection and estimation of iron.
Manufacture
It is synthesized by condensation of 2,6-dimethyl pyridine with 3,5-dinitrobenzenesulfonic acid, followed by reduction with Fe powder, and then sulfonation with fuming sulfuric acid. Purification occurs via crystallization from water.
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Synonym
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3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4´,4´´-disulfonic
acid sodium salt
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CAS no.
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28048-33-1
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EINECS no.
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248-797-6
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Molecular weight
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468.47 (anion)
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SPECIFICATIONS
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Test
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Unit
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Specification
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Appearance
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-
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Greenish yellow powder
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Solubility (C5%; w/v. in acetate buffer, pH 5.5)
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-
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Yellow, clear
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Identification by UV (c = 1%, w/v, d = 1 cm)
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-
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Should correspond to standard
Max 282-284 nm
Specific Extinction at absorption Max 385-465
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Identification by IR
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-
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Should correspond to standard
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Sodium by flame photometry, based on hydrous substance
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%
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4.0 -9.0
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KF Water
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%
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≤10.0
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Assay Ferrozine anion (Photometric), based on hydrous substance
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%
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90.0 -110.0
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APPLICATIONS
Determine the iron content in food, water, chemicals, and biological samples.
Study the metabolism of iron in cells and tissues.
Monitor the environmental pollution caused by heavy metals.
Preparation of iron complexes for catalysis.
Synthesis of iron nanoparticles for biomedicine.
Develop new sensors, biomaterials, and drug delivery systems.
Improve efficacy and safety of existing medicinal treatments.
Numerous other applications in scientific experiments, especially in the fields of analytical chemistry, biochemistry, and environmental science.
STORAGE
Stored at ambient temperature
PACKING
25 kg drum
REACH Status
Not registered yet